Professor Jeanne Tie is a clinician researcher and consultant medical oncologist specialising in the management of lower gastrointestinal cancers (colon, rectal and anal cancer). She is the Medical Oncology Lead for the Lower GI tumour stream at Peter MacCallum Cancer Centre and a senior research fellow within the division of personalised oncology at the Walter and Eliza Hall Institute. Following a clinical trial fellowship at the Royal Melbourne Hospital, her post-graduate research degree focused on the genomic biomarkers in colorectal cancer.
Her research interests are in clinical trials of novel therapeutics (early to late phase) and personalised cancer treatment for colorectal cancer, especially with the use of circulating tumour DNA (ctDNA). She is the principal investigator on many international clinical trials on novel therapy and leads several large national and international trials (DYNAMIC studies) using ctDNA to personalise treatment in localised colorectal cancer. She is also the lead investigator on the RESOLUTE trial assessing the benefit of integrating metastasis-directed local ablative therapies (surgery, stereotactic radiation, microwave ablation) with systemic treatment in oligometastatic colorectal cancer. She is passionate about multidisciplinary approach to cancer care and bringing scientific discoveries into the clinic by collaborating with surgeons, pathologists, radiologists, radiation oncologist and scientists.
She serves as the chair on the AGITG (Australasian Gastrointestinal Trials Group) Lower GI working party, member of AGITG’s Scientific Advisory Committee, ESMO Colorectal Tumour Faculty, several clinical trial steering committee and the Cancer Adjudication Committee for the ASPREE (Aspirin in Reducing Events in the Elderly) International study.
